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Happy Flour!
With plans to add folic acid to bread and flour to prevent neural tube defects, a study by researchers at the University of York and Hull have discovered a link between low levels of folate (a vitamin found in vegetables) and depression.
The Food Standards Agency recommended the introduction of fortification of bread or flour to help prevent defects that can lead to miscarriage, neonatal death and lifelong disability. The York study indicates that this measure could also assist in the battle against depression. Depression affects between 5% and 10% of people worldwide and is the third most common reason for people to visit their doctors.
This unique study is the first to collate evidence in this controversial area. Dr Gilroy said: "Although the research does not prove that low folate causes depression, we can now be sure that the two are linked. Interestingly, there is also some trial evidence that suggests folic acid supplements can benefit people with depression. We recommend that large trials should be carried out to further test this suggestion."
The same team published an article in the American Journal of Epidemiology proving that people with depression commonly have a gene that means that they process folate less efficiently. Folic acid is key to the process of manufacturing serotonin (the feel-good hormone) in the body.
This seemingly simple solution recommended for those planning a family could lead to help thousands of others suffering with depression without the need for anti-depressants.
For more information
Article: Gilroy S, Lightfoot T and Sheldon T. 'Is low folate a risk factor for depression? A meta-analysis and exploration of heterogeneity'. Journal of Epidemiology and Community Health 2007; 61: 631-637.
Article: Gilbody S, Lewis S and Lightfoot T. 'MTHFR polymorphisms and psychiatric disorders: a HuGE review'. American Journal of Epidemiology 2007; 165: 1-13.
Note: This story has been adapted from a news release issued by University of York.
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